Molecular characterization of fluoroquinolone resistance in invasive clinical isolates of <i>Streptococcus pneumoniae</i> susceptible to delafloxacin
Among LEV-R pneumococci, 71 (87%) were susceptible to delafloxacin, indicating that it maintains its activity despite the presence of mutations in gyrA + parC that lead to high-level resistance to levofloxacin.
Authors
- Marta Pérez-Abeledo (ORCID: https://orcid.org/0000-0002-5090-9437)
- Marta Iglesias (ORCID: https://orcid.org/0000-0001-7373-4927)
- Juan Carlos Sanz (ORCID: https://orcid.org/0000-0002-1453-8536)
- Laura Jiménez (ORCID: https://orcid.org/0000-0002-2176-0450)
- Emilia Cercenado (ORCID: https://orcid.org/0000-0002-5279-3773)
- Mercedes Marín (ORCID: https://orcid.org/0000-0001-8639-5215)
Institutions
- Universidad Complutense de Madrid (ES)
- Hospital General Universitario Gregorio Marañón (ES)
- Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (ES)
- Menarini Group (Italy) (IT)
- Comunidad de Madrid (ES)
Publication Details
- Journal
- Journal of Antimicrobial Chemotherapy
- Published
- 2025-08-07
- DOI
- https://doi.org/10.1093/jac/dkaf308
- Primary Topic
- Pneumonia and Respiratory Infections
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Menarini Group