Assessing the Efficacy of Cognitive Enhancers in Electroconvulsive Therapy: A Randomized Controlled Trial of Rivastigmine and Memantine
Rivastigmine may enhance cognitive recovery following ECT. Memantine showed a positive but nonsignificant effect. These findings support the potential utility of cholinergic modulation in mitigating ECT-related cognitive deficits. Future research should explore combination therapies and utilize more sensitive, domain-specific cognitive assessments.
Authors
- Alireza Shamsi (ORCID: https://orcid.org/0000-0002-2094-6229)
- Seyedeh Morvarid Neishabouri
- Maria Tavakoli-Ardakani
- Nafiseh Jahangiri Zarkani
- Parniyan Molaee
- Fateme Kazemi Khaledi
Institutions
- Pharmaceutical Sciences Research Center
- Shahid Beheshti University of Medical Sciences (IR)
Publication Details
- Journal
- Clinical Neuropharmacology
- Published
- 2025-08-08
- DOI
- https://doi.org/10.1097/wnf.0000000000000651
- Primary Topic
- Electroconvulsive Therapy Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00