Successful live birth via in vitro fertilization in a patient with lymphangioleiomyomatosis: a case report
This is the first case report presenting a female diagnosed with sporadic lymphangioleiomyomatosis and diminished ovarian reserve who successfully achieved a live birth via in vitro fertilization with no lymphangioleiomyomatosis-related complication. The use of low-estrogen protocols and multidisciplinary collaboration are essential to ensure maternal-fetal safety and to minimize the risk of lymphangioleiomyomatosis progression during controlled ovarian hyperstimulation and pregnancy.
Authors
- Yangjie Ou
- Yang Zeng (ORCID: https://orcid.org/0000-0002-4462-9711)
- Yunfeng Lin (ORCID: https://orcid.org/0000-0003-1224-6561)
- Yequn Chen (ORCID: https://orcid.org/0009-0008-6425-3847)
- Yanqiu Xie (ORCID: https://orcid.org/0000-0002-1080-7479)
- Xinyue Zhang (ORCID: https://orcid.org/0000-0001-6093-6335)
- Weilin Wang (ORCID: https://orcid.org/0000-0001-9432-2649)
- Haiying Wang (ORCID: https://orcid.org/0000-0002-1593-0708)
Institutions
- Guangdong Medical College (CN)
- Shantou University (CN)
- First Affiliated Hospital of Shantou University Medical College (CN)
- Shantou University Medical College (CN)
- Guangdong Academy of Medical Sciences (CN)
- Guangdong Provincial People's Hospital (CN)
- Southern Medical University (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Journal of Medical Case Reports
- Published
- 2025-08-22
- DOI
- https://doi.org/10.1186/s13256-025-05465-y
- Primary Topic
- Tuberous Sclerosis Complex Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- China Health Promotion Foundation