Investigation of the Effects of the Timing of Decompression and Topical Mitomycin-C Application on Nerve Regeneration in a Rat Model of Bell’s Palsy

FND can be effective in patients with total paralysis, even when performed in the late stages after allowing a period of recovery. Also, topical MMC applications aiming to reduce intraneural fibrosis have no effect on nerve regeneration.

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Publication Details

Journal
Turkish Archives of Otorhinolaryngology
Published
2025-08-22
DOI
https://doi.org/10.4274/tao.2025.2025-4-7
Primary Topic
Facial Nerve Paralysis Treatment and Research
Type
article
Field-Weighted Citation Impact
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article

Investigation of the Effects of the Timing of Decompression and Topical Mitomycin-C Application on Nerve Regeneration in a Rat Model of Bell’s Palsy

Said Sönmez, Beldan Polat, Cömert Şen, Nermi̇n Görkem Şi̇ri̇n et al.
Turkish Archives of Otorhinolaryngology
Facial Nerve Paralysis Treatment and Research
article

Investigation of the Effects of the Timing of Decompression and Topical Mitomycin-C Application on Nerve Regeneration in a Rat Model of Bell’s Palsy

Said Sönmez, Beldan Polat, Cömert Şen, Nermi̇n Görkem Şi̇ri̇n, Berkay Çaytemel, Gökçen Ünverengil, Elif Kocasoy Orhan, Kadir Serkan Orhan, Hakan Kara
article en

Abstract

FND can be effective in patients with total paralysis, even when performed in the late stages after allowing a period of recovery. Also, topical MMC applications aiming to reduce intraneural fibrosis have no effect on nerve regeneration.

Turkish Archives of OtorhinolaryngologyVol. 63(3)
Istanbul University (TR)
Openalex Percentile: Top 68%
Facial Nerve Paralysis Treatment and Research
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