Real‐World Impact on Postoperative Vomiting by Changing Anesthesia Regimens in Children Undergoing Strabismus Surgery: An Interrupted Time Series Analysis

Real-world departmental-level data showed a decrease in POV occurrence after transitioning from sevoflurane-based anesthesia with pentazocine to propofol/opioid TIVA with DEX. However, no significant decrease in POV occurrence was found by adding OND to propofol/opioid TIVA with DEX. Further studies are needed to improve the generalizability of evaluating the real-world antiemetic effect of combining antiemetic medications on propofol/opioid TIVA.

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Publication Details

Journal
Pediatric Anesthesia
Published
2025-08-22
DOI
https://doi.org/10.1111/pan.70041
Primary Topic
Nausea and vomiting management
Type
article
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article

Real‐World Impact on Postoperative Vomiting by Changing Anesthesia Regimens in Children Undergoing Strabismus Surgery: An Interrupted Time Series Analysis

Taiki Kojima, Soichiro Obara, Aya Sueda, Takashi Fujiwara et al.
Pediatric Anesthesia
Nausea and vomiting management
article

Real‐World Impact on Postoperative Vomiting by Changing Anesthesia Regimens in Children Undergoing Strabismus Surgery: An Interrupted Time Series Analysis

Taiki Kojima, Soichiro Obara, Aya Sueda, Takashi Fujiwara, Yusuke Yamauchi, Sayuri Yasuda
article en

Abstract

Real-world departmental-level data showed a decrease in POV occurrence after transitioning from sevoflurane-based anesthesia with pentazocine to propofol/opioid TIVA with DEX. However, no significant decrease in POV occurrence was found by adding OND to propofol/opioid TIVA with DEX. Further studies are needed to improve the generalizability of evaluating the real-world antiemetic effect of combining antiemetic medications on propofol/opioid TIVA.

Pediatric AnesthesiaVol. 36(1)
Nagoya University Hospital (JP), Kobe Children's Hospital (JP), Nagoya University (JP), Teikyo University (JP)
Openalex Percentile: Top 65%
Nausea and vomiting management
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