Pharmacokinetic study of the synthetic cannabinoid, 5F-MDMB-PICA, in male Wistar rats

A precise and accurate GC-MS method was successfully developed and validated for the quantification of 5F-MDMB-PICA in rat plasma, enabling comprehensive assessment of its pharmacokinetics, bioavailability, and tissue distribution. These results provide valuable insights that may enhance the understanding of the pharmacokinetic and pharmacodynamic profiles of 5F-MDMB-PICA.

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Publication Details

Journal
Indian Journal of Pharmacology
Published
2025-08-22
DOI
https://doi.org/10.4103/ijp.ijp_226_24
Primary Topic
Forensic Toxicology and Drug Analysis
Type
article
Field-Weighted Citation Impact
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article

Pharmacokinetic study of the synthetic cannabinoid, 5F-MDMB-PICA, in male Wistar rats

Sachil Kumar, Bijad Alharbi, Elkhatim Hassan Abdelgadir, Noor Hassan Dammas
Indian Journal of Pharmacology
Forensic Toxicology and Drug Analysis
article

Pharmacokinetic study of the synthetic cannabinoid, 5F-MDMB-PICA, in male Wistar rats

Sachil Kumar, Bijad Alharbi, Elkhatim Hassan Abdelgadir, Noor Hassan Dammas
article en

Abstract

A precise and accurate GC-MS method was successfully developed and validated for the quantification of 5F-MDMB-PICA in rat plasma, enabling comprehensive assessment of its pharmacokinetics, bioavailability, and tissue distribution. These results provide valuable insights that may enhance the understanding of the pharmacokinetic and pharmacodynamic profiles of 5F-MDMB-PICA.

Indian Journal of PharmacologyVol. 57(5)
Amity University (IN), Naif Arab University for Security Sciences (SA)
Openalex Percentile: Top 79%
Forensic Toxicology and Drug Analysis
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