Investigating the Influence of Experimentally Induced Secondary Hyperalgesia on Pain Prediction Error Encoding in Healthy Individuals: A Novel Virtual Reality Protocol
We introduce a novel VR paradigm to show that secondary hyperalgesia alters how pain expectations and prediction errors influence pain perception, highlighting distinct adaptive learning patterns.
Authors
- Sam Hughes (ORCID: https://orcid.org/0000-0002-3769-3803)
- Sonia Medina (ORCID: https://orcid.org/0000-0001-8883-6520)
- Federico Palmisani (ORCID: https://orcid.org/0000-0001-5818-4007)
- Jawahar Sri Prakash Thiyagarajan
- Joe Horsey
Institutions
- University of Exeter (GB)
Publication Details
- Journal
- European Journal of Pain
- Published
- 2025-08-22
- DOI
- https://doi.org/10.1002/ejp.70113
- Primary Topic
- Pain Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institute for Health and Care Research
- Department of Health and Social Care
- Academy of Medical Sciences