Asbestos bodies and amphibole fibres in the lung: do the Helsinki criteria need an update?

Based on a large sample size, we have shown good sensitivity for AB but very low sensitivity for AAF using Helsinki criteria for the attribution of exposure to asbestos. We propose to adopt lower values (600 AB or 300,000 AAF), because they would avoid a large proportion of false negatives. We remind that lung fibre burden analysis should be viewed as a complement (not a substitute) for a carefully collected lifetime job history.

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Institutions

Publication Details

Journal
Annals of Work Exposures and Health
Published
2025-08-03
DOI
https://doi.org/10.1093/annweh/wxaf047
Citations
2
Primary Topic
Occupational and environmental lung diseases
Type
article
Field-Weighted Citation Impact
3.04
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article

Asbestos bodies and amphibole fibres in the lung: do the Helsinki criteria need an update?

Anna Somigliana, Ugo Fedeli, Dario Consonni, Paolo Girardi et al.
2 citations
Annals of Work Exposures and Health
Occupational and environmental lung diseases
3.04
article

Asbestos bodies and amphibole fibres in the lung: do the Helsinki criteria need an update?

Anna Somigliana, Ugo Fedeli, Dario Consonni, Paolo Girardi, Anna Muran, Pietro Gino Barbieri, Donatella Calligaro
article en
2 citations

Abstract

Based on a large sample size, we have shown good sensitivity for AB but very low sensitivity for AAF using Helsinki criteria for the attribution of exposure to asbestos. We propose to adopt lower values (600 AB or 300,000 AAF), because they would avoid a large proportion of false negatives. We remind that lung fibre burden analysis should be viewed as a complement (not a substitute) for a carefully collected lifetime job history.

Annals of Work Exposures and HealthVol. 69(8)
Agenzia Regionale per la Protezione Ambientale del Piemonte (IT), Ca' Foscari University of Venice (IT), Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico (IT), Departamento de Epidemiología (GT), Regional Health (US), Regione del Veneto (IT), Azienda Sanitaria Universitaria Integrata di Trieste (IT)
Openalex Percentile: Top 8%
Occupational and environmental lung diseases
3.04
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Asbestos bodies and amphibole fibres in the lung: do the Helsinki criteria need an update? — Anna Somigliana, Ugo Fedeli, et al. · Annals of Work Exposures and Health (2025) | TGRS Research Map | TGRS