Comparison of Two α‐Synuclein Seed Amplification Assays for Discrimination of Parkinson Disease and Atypical Parkinsonism
Amprion-SAA, performed at ISNB, uniquely discriminated MSA from both PD and PSP participants with good accuracy. However, it showed lower specificity than ISNB-SAA, primarily related to the type 2 profile. © 2025 The Author(s). Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.
Authors
- Simone Baiardi (ORCID: https://orcid.org/0000-0002-7702-7856)
- Piero Parchi (ORCID: https://orcid.org/0000-0002-9444-9524)
- Luis Concha‐Marambio (ORCID: https://orcid.org/0000-0002-9454-8389)
- Luisa Sambati (ORCID: https://orcid.org/0000-0002-5939-7933)
- Yihua Ma (ORCID: https://orcid.org/0000-0002-5664-8178)
- Marcello Rossi (ORCID: https://orcid.org/0000-0002-8125-6571)
- Franco Magliocchetti (ORCID: https://orcid.org/0009-0004-3894-8419)
- Giovanna Calandra–Buonaura (ORCID: https://orcid.org/0000-0002-9447-3532)
- Giulia Giannini (ORCID: https://orcid.org/0000-0002-0499-3236)
- Carly M. Farris (ORCID: https://orcid.org/0000-0002-8277-8531)
- Erica Vittoriosi
Institutions
- Amprion (United States) (US)
- Istituto delle Scienze Neurologiche di Bologna (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- University of Bologna (IT)
Publication Details
- Journal
- Movement Disorders
- Published
- 2025-08-20
- DOI
- https://doi.org/10.1002/mds.70017
- Citations
- 1
- Primary Topic
- Parkinson's Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- Michael J. Fox Foundation for Parkinson's Research
- Ministero della Salute
- Ministero dell'Università e della Ricerca