Multifunctional Nanocomposites for Efficient Gene Delivery

With the continuous development of gene therapy technology, an efficient gene delivery system has become the key to realizing gene therapy. Traditional gene delivery methods have many limitations, such as low transfection efficiency and high cytotoxicity. As a new type of gene delivery vector, multifunctional nanocomposites have shown great application potential due to their unique physical and chemical properties and biocompatibility. This paper aims to study the application of multifunctional nanocomposites in gene delivery through the analysis of relevant cases and the discussion of their mechanism of action to understand their advantages and challenges in gene therapy deeply. The results show that the multifunctional nanocomposites can effectively improve gene transfection efficiency, reduce cytotoxicity, and achieve targeted gene delivery. In addition, its application in the treatment of different diseases has been explored. The research significance of this paper is to provide a theoretical basis and practical guidance for the further development of multifunctional nanocomposites in the field of gene therapy and promote the clinical application of gene therapy technology.

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Publication Details

Journal
Highlights in Science Engineering and Technology
Published
2025-07-11
DOI
https://doi.org/10.54097/zg390z62
Primary Topic
RNA Interference and Gene Delivery
Type
article
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article

Multifunctional Nanocomposites for Efficient Gene Delivery

Yi‐Ting Wang
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Highlights in Science Engineering and Technology
RNA Interference and Gene Delivery
article

Multifunctional Nanocomposites for Efficient Gene Delivery

Yi‐Ting Wang
article en

Abstract

With the continuous development of gene therapy technology, an efficient gene delivery system has become the key to realizing gene therapy. Traditional gene delivery methods have many limitations, such as low transfection efficiency and high cytotoxicity. As a new type of gene delivery vector, multifunctional nanocomposites have shown great application potential due to their unique physical and chemical properties and biocompatibility. This paper aims to study the application of multifunctional nanocomposites in gene delivery through the analysis of relevant cases and the discussion of their mechanism of action to understand their advantages and challenges in gene therapy deeply. The results show that the multifunctional nanocomposites can effectively improve gene transfection efficiency, reduce cytotoxicity, and achieve targeted gene delivery. In addition, its application in the treatment of different diseases has been explored. The research significance of this paper is to provide a theoretical basis and practical guidance for the further development of multifunctional nanocomposites in the field of gene therapy and promote the clinical application of gene therapy technology.

Highlights in Science Engineering and TechnologyVol. 147
Tongji University (CN), Shanghai University of Finance and Economics (CN)
Openalex Percentile: Top 81%
RNA Interference and Gene Delivery
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