Efficacy of Topical Sialogogues in Xerostomia Treatment on Chronic Residents of C.H.P.L.

Institutionalized psychiatric patients on chronic psychotropic medication are prone to xerostomia due to reduced salivary flow. This study evaluated the effectiveness of a topical sialogogue gel (Xeros Dentaid®) in relieving drug-induced dry mouth in 81 residents at the Lisbon Psychiatric Hospital Centre (C.H.P.L.). Over 15 days, unstimulated and stimulated salivary flow rates, pH, and buffer capacity were measured before and after application. Results showed a significant increase in salivary flow (p < 0.001) and improved subjective symptoms. Topical sialogogues may represent an accessible and effective strategy for managing xerostomia in this vulnerable population.

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Published
2025-08-20
DOI
https://doi.org/10.3390/msf2025037006
Primary Topic
Salivary Gland Disorders and Functions
Type
article
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article

Efficacy of Topical Sialogogues in Xerostomia Treatment on Chronic Residents of C.H.P.L.

Ana Cristina Manso, Cecília Rozan, Edna Verissimo
Salivary Gland Disorders and Functions
article

Efficacy of Topical Sialogogues in Xerostomia Treatment on Chronic Residents of C.H.P.L.

Ana Cristina Manso, Cecília Rozan, Edna Verissimo
article en

Abstract

Institutionalized psychiatric patients on chronic psychotropic medication are prone to xerostomia due to reduced salivary flow. This study evaluated the effectiveness of a topical sialogogue gel (Xeros Dentaid®) in relieving drug-induced dry mouth in 81 residents at the Lisbon Psychiatric Hospital Centre (C.H.P.L.). Over 15 days, unstimulated and stimulated salivary flow rates, pH, and buffer capacity were measured before and after application. Results showed a significant increase in salivary flow (p < 0.001) and improved subjective symptoms. Topical sialogogues may represent an accessible and effective strategy for managing xerostomia in this vulnerable population.

Escola Superior de Saúde Egas Moniz (PT)
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Openalex Percentile: Top 73%
Salivary Gland Disorders and Functions
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Efficacy of Topical Sialogogues in Xerostomia Treatment on Chronic Residents of C.H.P.L. — Ana Cristina Manso, Cecília Rozan, et al. · (2025) | TGRS Research Map | TGRS