Pacing-Induced Cardiomyopathy Following Permanent Pacemaker Implantation: A Case Report and Review of Management Strategies

Pacing-induced cardiomyopathy (PICM) is a well-documented complication of long-term right ventricular pacing (RVP) leading to left ventricular systolic dysfunction and heart failure. We describe a 58-year-old woman with a history of complete heart block who underwent single-chamber pacemaker implantation. Eleven months later, she presented with New York Heart Association (NYHA) class IV heart failure and bilateral pleural effusions. Investigations revealed a significant drop in ejection fraction from 55% to 25%, with no other identifiable cause of heart failure. She was diagnosed with PICM and successfully managed with medical therapy and upgrade to cardiac resynchronisation therapy pacemaker (CRT-P). Her clinical symptoms and left ventricular function improved significantly. This case highlights the importance of early recognition of PICM and the benefit of CRT-P upgrade in patients with high RVP burden.

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Journal
Cureus
Published
2025-08-20
DOI
https://doi.org/10.7759/cureus.90624
Primary Topic
Cardiac pacing and defibrillation studies
Type
article
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article

Pacing-Induced Cardiomyopathy Following Permanent Pacemaker Implantation: A Case Report and Review of Management Strategies

Sujani Madhurika Kodagoda Gamage, N Dahanayake, Tiron Chathuranga
Cureus
Cardiac pacing and defibrillation studies
article

Pacing-Induced Cardiomyopathy Following Permanent Pacemaker Implantation: A Case Report and Review of Management Strategies

Sujani Madhurika Kodagoda Gamage, N Dahanayake, Tiron Chathuranga
article en

Abstract

Pacing-induced cardiomyopathy (PICM) is a well-documented complication of long-term right ventricular pacing (RVP) leading to left ventricular systolic dysfunction and heart failure. We describe a 58-year-old woman with a history of complete heart block who underwent single-chamber pacemaker implantation. Eleven months later, she presented with New York Heart Association (NYHA) class IV heart failure and bilateral pleural effusions. Investigations revealed a significant drop in ejection fraction from 55% to 25%, with no other identifiable cause of heart failure. She was diagnosed with PICM and successfully managed with medical therapy and upgrade to cardiac resynchronisation therapy pacemaker (CRT-P). Her clinical symptoms and left ventricular function improved significantly. This case highlights the importance of early recognition of PICM and the benefit of CRT-P upgrade in patients with high RVP burden.

CureusVol. 17(8)
University of Ruhuna (LK), University of St.Gallen (CH)
Openalex Percentile: Top 66%
Cardiac pacing and defibrillation studies
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Pacing-Induced Cardiomyopathy Following Permanent Pacemaker Implantation: A Case Report and Review of Management Strategies — Sujani Madhurika Kodagoda Gamage, N Dahanayake, et al. · Cureus (2025) | TGRS Research Map | TGRS