Trajectories of Selective Serotonin Reuptake Inhibitor Use in Pregnancy and Perinatal Outcomes: A Longitudinal Register Study
SSRI use up to standard doses was not associated with adverse perinatal outcomes. However, linear dose-response associations and sustained higher doses suggest potentially reduced placental efficacy and increased risk of adverse perinatal health, warranting caution.
Authors
- Maiju Pesonen (ORCID: https://orcid.org/0000-0002-3399-2136)
- Guro Pauck Bernhardsen (ORCID: https://orcid.org/0000-0003-1622-2911)
- Leea Keski‐Nisula (ORCID: https://orcid.org/0000-0002-5354-0700)
- Soili M. Lehto (ORCID: https://orcid.org/0000-0003-4324-6679)
Institutions
- Oslo University Hospital (NO)
- Norwegian Institute of Public Health (NO)
- University of Eastern Finland (FI)
- University of Oslo (NO)
- Akershus University Hospital (NO)
- Kuopio University Hospital (FI)
Publication Details
- Journal
- BJOG An International Journal of Obstetrics & Gynaecology
- Published
- 2025-08-20
- DOI
- https://doi.org/10.1111/1471-0528.18337
- Primary Topic
- Maternal Mental Health During Pregnancy and Postpartum
- Type
- article
- Field-Weighted Citation Impact
- 0.00