A Comparative Clinical Evaluation of Pathyadi Churna and Erand Tail (Castor Oil) in the Management of Amavat (Rheumatoid Arthritis) with Special References to Gut Microbiome

The concept of Kaya (Agni) is unique and is responsible for bio- transformation. As it is known that energy can neither be created nor can it be destroyed. In human body, Kaya provides the necessary energy for all bodily activities. The energy provided is derived from the food we eat and the air we breathe. The biological system of the body transforms this energy to one, which is utilized by the cells. It encompasses knowledge about dispensing, dose and duration of medicine. The principles of Kayachikitsa correct Agni, Dosha, Dhatu and detoxify body thus help to cure general diseases. The rejuvenation therapy (Rasayana) of Kayachikitsa also restores physical and mental health status. The basic principles of Kayachikitsa provide ways for the management of diseases related to the disturbed pattern of lifestyle i.e. metabolic disorders. The Kayachikitsa helps to manage various metabolic disorders including obesity, hypertension, high cholesterol, fatty liver, diabetes and digestive problems. These diseases mainly occur due to the disturbed pattern of daily regimen such as irregular diet, physical exertion, stress, disturbed sleeping patterns, bad dietary habits, anger and lack of exercise, etc. The drugs such as Haritaki, Amalaki, Vibhitaki Guggulu Resin, Vidanga, Morus Indica, Gymnema Sylvestre, Kalonji and Eugenia Jambolana, etc. these are used as single drug choice or as a raw material for a specific formulation such as Pathyadichurna and Arand tail on which this study has been made in favour to access comparative clinical evaluation Amavat(Rheumatoid Arthritis) with Special References to Gut microbiome.