Figure 4 from Gut Microbiome Profiling in Eμ-TCL1 Mice Reveals Intestinal Changes and a Dysbiotic Signature Specific to Chronic Lymphocytic Leukemia
<p>Differential expression of markers pertaining to intestinal integrity and inflammation in WT B6 and Eμ-TCL1 mice. ELISA was used to assess the concentration of tight junction markers in plasma of 12-month-old WT B6 and Eμ-TCL1 mice: CLDN2 (<b>A</b>), CLDN3 (<b>B</b>), zonulin (<b>C</b>), and sCD14 (<b>D</b>). Asterisks denote significance between WT B6 and Eμ-TCL1 mice (**, <i>P</i> < 0.01; ***, <i>P</i> < 0.001). Unpaired Welch <i>t</i> test was applied for testing.</p>
Authors
- Christopher R. D’Angelo (ORCID: https://orcid.org/0000-0001-8456-0889)
- Alexandria P. Eiken (ORCID: https://orcid.org/0000-0003-0161-7814)
- Punita Dhawan (ORCID: https://orcid.org/0000-0003-3434-8155)
- Elizabeth Schmitz (ORCID: https://orcid.org/0000-0002-9619-5193)
- Kathryn Cooper (ORCID: https://orcid.org/0000-0002-6341-9648)
- Audrey L. Smith (ORCID: https://orcid.org/0000-0001-5096-5351)
- Geoffrey A. Talmon (ORCID: https://orcid.org/0000-0002-4841-286X)
- Grinu Mathew (ORCID: https://orcid.org/0000-0001-6115-6373)
- Mark Primeaux (ORCID: https://orcid.org/0000-0001-7589-3745)
- Sydney A. Skupa
- Erin M. Drengler
- Dalia El-Gamal
- Grace M. Waldron (ORCID: https://orcid.org/0000-0002-9711-8464)
Publication Details
- Published
- 2025-08-15
- DOI
- https://doi.org/10.1158/2767-9764.29917554
- Primary Topic
- Digestive system and related health
- Type
- article
- Field-Weighted Citation Impact
- 0.00