The gender-sensitive spectrum of neurodevelopmental disorders: a case report on a ZMYM3 variant in a 19-year-old female

This case contributes to the limited literature on <i>ZMYM3</i>-related NDDs in females, highlighting potential variability in phenotypic expression due to X-inactivation and penetrance effects. The patient's symptoms emphasize how ADHD and other neurodevelopmental traits may manifest differently in females, often with more subtle and internalized features. Our findings underscore the importance of sex-specific research on <i>ZMYM3</i>-associated disorders and the need for comprehensive genetic and neuropsychological assessments to guide diagnosis and intervention in affected individuals.