Transcription factor ETV1 promotes angiogenesis after myocardial infarction via activation of the VEGFA/VEGFR2/eNOS pathway
In summary, Etv1 promote angiogenesis via activating VEGFA/VEGFR2/eNOS pathway after MI, which further ameliorate adverse ventricular remodeling. These results suggest that ETV1 may serve as a potential target for the treatment of myocardial infarction.
Authors
- Chen Yuan (ORCID: https://orcid.org/0000-0002-3730-8397)
- Feng Li (ORCID: https://orcid.org/0000-0003-0841-6329)
- Jinyu Wang (ORCID: https://orcid.org/0000-0001-5689-6174)
- Chunxia Li (ORCID: https://orcid.org/0000-0002-0413-882X)
- Sen Fang
Institutions
- Shanxi Medical University (CN)
- Shanxi Academy of Medical Sciences (CN)
- Tongji Hospital (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Frontiers in Cardiovascular Medicine
- Published
- 2025-08-15
- DOI
- https://doi.org/10.3389/fcvm.2025.1633438
- Primary Topic
- Cardiac Fibrosis and Remodeling
- Type
- article
- Field-Weighted Citation Impact
- 0.00