Irisin alleviated sepsis via enhancing macrophage phagocytosis and reducing inflammation levels
Irisin improves splenic macrophage phagocytosis and reduces macrophage inflammation, thereby mitigating sepsis. Irisin holds potential as a therapeutic agent for sepsis treatment.
Authors
- Yunyan Ji
- Zeen Gong (ORCID: https://orcid.org/0000-0003-2856-3318)
- Xiaomao Luo (ORCID: https://orcid.org/0000-0001-8563-8211)
- Haiyang Wu
- Jiayin Lu
- Juan Wang (ORCID: https://orcid.org/0000-0003-1389-8326)
- Yanjun Dong (ORCID: https://orcid.org/0000-0001-6396-8949)
- Xiuju Yu
- Linli Xue
- Haidong Wang (ORCID: https://orcid.org/0009-0002-6907-7172)
- Yi Yan (ORCID: https://orcid.org/0000-0002-0982-0713)
Institutions
- Shanxi Agricultural University (CN)
- Shanghai Chest Hospital (CN)
- China Agricultural University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-08-15
- DOI
- https://doi.org/10.3389/fimmu.2025.1618699
- Primary Topic
- Adipose Tissue and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Shanxi Agricultural University