Multilayer Neural-Network-Based EEG Analysis for the Detection of Epilepsy, Migraine, and Schizophrenia

The early detection of neurological and psychiatric disorders is critical for optimizing patient outcomes and improving the efficacy of healthcare delivery. This study presents a novel multiclass machine learning (ML) framework designed to classify epilepsy, migraine, and schizophrenia simultaneously using electroencephalography (EEG) signals. Unlike conventional approaches that predominantly rely on binary classification (e.g., healthy vs. diseased cohorts), this work addresses a significant gap in the literature by introducing a unified artificial neural network (ANN) architecture capable of discriminating among three distinct neurological and psychiatric conditions. The proposed methodology involves decomposing raw EEG signals into constituent frequency subbands to facilitate robust feature extraction. These discriminative features were subsequently classified using a multilayer ANN, achieving performance metrics of 95% sensitivity, 96% specificity, and a 95% F1-score. To enhance clinical applicability, the model was optimized for potential integration into real-time diagnostic systems, thereby supporting the development of a rapid, reliable, and scalable decision support tool. The results underscore the viability of EEG-based multiclass models as a promising diagnostic aid for neurological and psychiatric disorders. By consolidating the detection of multiple conditions within a single computational framework, this approach offers a scalable and efficient alternative to traditional binary classification paradigms.

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Publication Details

Journal
Applied Sciences
Published
2025-08-14
DOI
https://doi.org/10.3390/app15168983
Citations
2
Primary Topic
EEG and Brain-Computer Interfaces
Type
article
Field-Weighted Citation Impact
2.86

Funders

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article

Multilayer Neural-Network-Based EEG Analysis for the Detection of Epilepsy, Migraine, and Schizophrenia

Mehmet Ufuk Aluçlu, Ibrahim H. Dursun, Betül Uyar, Mehmet Akın
2 citations
Applied Sciences
EEG and Brain-Computer Interfaces
2.86
article

Multilayer Neural-Network-Based EEG Analysis for the Detection of Epilepsy, Migraine, and Schizophrenia

Mehmet Ufuk Aluçlu, Ibrahim H. Dursun, Betül Uyar, Mehmet Akın
article en
2 citations

Abstract

The early detection of neurological and psychiatric disorders is critical for optimizing patient outcomes and improving the efficacy of healthcare delivery. This study presents a novel multiclass machine learning (ML) framework designed to classify epilepsy, migraine, and schizophrenia simultaneously using electroencephalography (EEG) signals. Unlike conventional approaches that predominantly rely on binary classification (e.g., healthy vs. diseased cohorts), this work addresses a significant gap in the literature by introducing a unified artificial neural network (ANN) architecture capable of discriminating among three distinct neurological and psychiatric conditions. The proposed methodology involves decomposing raw EEG signals into constituent frequency subbands to facilitate robust feature extraction. These discriminative features were subsequently classified using a multilayer ANN, achieving performance metrics of 95% sensitivity, 96% specificity, and a 95% F1-score. To enhance clinical applicability, the model was optimized for potential integration into real-time diagnostic systems, thereby supporting the development of a rapid, reliable, and scalable decision support tool. The results underscore the viability of EEG-based multiclass models as a promising diagnostic aid for neurological and psychiatric disorders. By consolidating the detection of multiple conditions within a single computational framework, this approach offers a scalable and efficient alternative to traditional binary classification paradigms.

Applied SciencesVol. 15(16)
Dicle University (TR)
Dicle Üniversitesi
Openalex Percentile: Top 9%
EEG and Brain-Computer Interfaces
2.86
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