Predicting Chronic Kidney Disease After Cisplatin Treatment Using Population-Level Data
This study found that cisplatin treatment was followed by a predictable decrease in the eGFR, placing patients with a lower baseline eGFR at the highest risk of CKD. A simple model based on the pretreatment eGFR predicts CKD risk and could guide clinical decision-making.
Authors
- Jiang Chen He (ORCID: https://orcid.org/0000-0002-9512-4975)
- Steven Gallinger (ORCID: https://orcid.org/0000-0002-6998-9414)
- Ning Liu (ORCID: https://orcid.org/0000-0001-9215-475X)
- Andrea Knežević (ORCID: https://orcid.org/0000-0002-0741-2150)
- Abhijat Kitchlu (ORCID: https://orcid.org/0000-0002-4340-5046)
- Marzyeh Ghassemi
- Edgar A. Jaimes (ORCID: https://orcid.org/0000-0002-5756-5120)
- Sheron Latcha (ORCID: https://orcid.org/0000-0001-5159-9680)
- Faiyaz Notta (ORCID: https://orcid.org/0000-0002-5748-3985)
- Robert C. Grant (ORCID: https://orcid.org/0000-0002-9821-0377)
- Sho Podolsky
- Kelvin Chan
Institutions
- Ontario Institute for Cancer Research (CA)
- Sunnybrook Health Science Centre (CA)
- University Health Network (CA)
- Memorial Sloan Kettering Cancer Center (US)
- Health Sciences Centre (CA)
- Princess Margaret Cancer Centre (CA)
- Institute for Clinical Evaluative Sciences (CA)
- Massachusetts Institute of Technology (US)
Publication Details
- Journal
- JAMA Oncology
- Published
- 2025-08-21
- DOI
- https://doi.org/10.1001/jamaoncol.2025.2590
- Citations
- 1
- Primary Topic
- Chemotherapy-induced organ toxicity mitigation
- Type
- article
- Field-Weighted Citation Impact
- 1.47