Low-dose extracorporeal shock wave attenuates sepsis-related acute lung injury by targeting mitochondrial dysfunction and pyroptosis crosstalk in type II alveolar epithelial cells
This study reveals that SW attenuates septic ALI by targeting mitochondrial-pyroptosis crosstalk, offering a novel non-invasive therapeutic strategy for clinical applications.
Authors
- Ruidong Ge (ORCID: https://orcid.org/0000-0002-6082-8032)
- Jianning Guo (ORCID: https://orcid.org/0000-0003-0926-0119)
- Dan Lv (ORCID: https://orcid.org/0000-0002-8029-0110)
- Lijuan Tang
- Hui Qin (ORCID: https://orcid.org/0000-0002-6369-7488)
- Fang Ye
- Xiaoxuan Qu
- Yuanmei Chen (ORCID: https://orcid.org/0000-0002-3804-731X)
- Qi Zhang (ORCID: https://orcid.org/0000-0002-8881-7079)
- Jing Liu (ORCID: https://orcid.org/0000-0003-4699-1375)
- Chao Wang (ORCID: https://orcid.org/0000-0002-8054-3472)
- Die Liu (ORCID: https://orcid.org/0009-0005-0169-5769)
- Meihong Xia
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- China-Japan Friendship Hospital (CN)
- Peking Union Medical College Hospital (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-08-21
- DOI
- https://doi.org/10.3389/fimmu.2025.1637378
- Citations
- 1
- Primary Topic
- Inflammasome and immune disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- China-Japan Friendship Hospital