Inside Front Cover: Visual β‐Sheet‐to‐β‐Turn Transition in Luminescent Polymeric Vesicles for Color‐Reporting Drug Delivery (Angew. Chem. Int. Ed. 37/2025)

A tetraphenylethylene-conjugated poly(L-cysteine) vesicle was engineered to execute a β-sheet-to-β-turn conformational transformation driven by reactive oxygen species-mediated thioether oxidation, as reported by Mingming Ding et al. (e202503875). The transition boosted fluorescence and circularly polarized luminescence, enabling dual-modal tracking of conformational changes, and mediated a full color-reportable drug release, allowing efficient imaging and treatment of tumors.

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Publication Details

Journal
Angewandte Chemie International Edition
Published
2025-08-21
DOI
https://doi.org/10.1002/anie.202517894
Primary Topic
Luminescence and Fluorescent Materials
Type
article
Field-Weighted Citation Impact
0.00
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article

Inside Front Cover: Visual β‐Sheet‐to‐β‐Turn Transition in Luminescent Polymeric Vesicles for Color‐Reporting Drug Delivery (Angew. Chem. Int. Ed. 37/2025)

Zifen Li, Zuojie Wang, Mingming Ding, Yang Liu et al.
Angewandte Chemie International Edition
Luminescence and Fluorescent Materials
article

Inside Front Cover: Visual β‐Sheet‐to‐β‐Turn Transition in Luminescent Polymeric Vesicles for Color‐Reporting Drug Delivery (Angew. Chem. Int. Ed. 37/2025)

Zifen Li, Zuojie Wang, Mingming Ding, Yang Liu, Yiwei Wang, Chuan Peng, Xiaohan Dong, Yi Zheng, Yeqiang Zhou
article en

Abstract

A tetraphenylethylene-conjugated poly(L-cysteine) vesicle was engineered to execute a β-sheet-to-β-turn conformational transformation driven by reactive oxygen species-mediated thioether oxidation, as reported by Mingming Ding et al. (e202503875). The transition boosted fluorescence and circularly polarized luminescence, enabling dual-modal tracking of conformational changes, and mediated a full color-reportable drug release, allowing efficient imaging and treatment of tumors.

Angewandte Chemie International EditionVol. 64(37)
Sichuan University (CN)
Good health and well-being
Openalex Percentile: Top 84%
Luminescence and Fluorescent Materials
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