Inside Front Cover: Visual β‐Sheet‐to‐β‐Turn Transition in Luminescent Polymeric Vesicles for Color‐Reporting Drug Delivery (Angew. Chem. Int. Ed. 37/2025)
A tetraphenylethylene-conjugated poly(L-cysteine) vesicle was engineered to execute a β-sheet-to-β-turn conformational transformation driven by reactive oxygen species-mediated thioether oxidation, as reported by Mingming Ding et al. (e202503875). The transition boosted fluorescence and circularly polarized luminescence, enabling dual-modal tracking of conformational changes, and mediated a full color-reportable drug release, allowing efficient imaging and treatment of tumors.
Authors
- Zifen Li
- Zuojie Wang
- Mingming Ding (ORCID: https://orcid.org/0000-0002-9877-7699)
- Yang Liu (ORCID: https://orcid.org/0000-0001-5752-5180)
- Yiwei Wang (ORCID: https://orcid.org/0000-0003-2679-8623)
- Chuan Peng
- Xiaohan Dong (ORCID: https://orcid.org/0000-0003-4140-1284)
- Yi Zheng
- Yeqiang Zhou
Institutions
- Sichuan University (CN)
Publication Details
- Journal
- Angewandte Chemie International Edition
- Published
- 2025-08-21
- DOI
- https://doi.org/10.1002/anie.202517894
- Primary Topic
- Luminescence and Fluorescent Materials
- Type
- article
- Field-Weighted Citation Impact
- 0.00