Defocus correction and noise reduction using a hybrid ptychography and Centre‐of‐Mass algorithm

Integrated Centre-of-Mass (iCOM) is a widely used phase-contrast imaging method based on Centre-of-Mass (COM), which makes use of a 4D Scanning Transmission Electron Microscopy (STEM) dataset using an in-focus probe. In this paper, we introduce a novel approach that combines Single-Side Band (SSB) ptychography with COM and iCOM, termed Side Band masked Centre-of-Mass (SBm-COM) and integrated Centre-of-Mass (SBm-iCOM) which is applicable to weak-phase objects. This method compensates for residual aberrations in 4DSTEM datasets while also reducing the noise contribution up to the <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"> <mml:semantics><mml:mrow><mml:mn>2</mml:mn> <mml:mi>α</mml:mi></mml:mrow> <mml:annotation>$2\alpha $</mml:annotation></mml:semantics> </mml:math> resolution limit. The aberration compensation and noise filtering features make the SBm-(i)COM suitable for samples that are difficult to focus or those that require minimal electron fluence. SBm-iCOM transfers the same information as SSB ptychography but results in an intrinsic transfer function that enhances low-frequency information.

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Publication Details

Journal
Journal of Microscopy
Published
2025-08-21
DOI
https://doi.org/10.1111/jmi.70010
Citations
2
Primary Topic
Advanced X-ray Imaging Techniques
Type
article
Field-Weighted Citation Impact
3.77
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article

Defocus correction and noise reduction using a hybrid ptychography and Centre‐of‐Mass algorithm

Chen Huang, Peter D. Nellist, Adrián Pedrazo‐Tardajos, Angus I. Kirkland et al.
2 citations
Journal of Microscopy
Advanced X-ray Imaging Techniques
3.77
article

Defocus correction and noise reduction using a hybrid ptychography and Centre‐of‐Mass algorithm

Chen Huang, Peter D. Nellist, Adrián Pedrazo‐Tardajos, Angus I. Kirkland, Zhiyuan Ding
article en
2 citations

Abstract

Integrated Centre-of-Mass (iCOM) is a widely used phase-contrast imaging method based on Centre-of-Mass (COM), which makes use of a 4D Scanning Transmission Electron Microscopy (STEM) dataset using an in-focus probe. In this paper, we introduce a novel approach that combines Single-Side Band (SSB) ptychography with COM and iCOM, termed Side Band masked Centre-of-Mass (SBm-COM) and integrated Centre-of-Mass (SBm-iCOM) which is applicable to weak-phase objects. This method compensates for residual aberrations in 4DSTEM datasets while also reducing the noise contribution up to the <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"> <mml:semantics><mml:mrow><mml:mn>2</mml:mn> <mml:mi>α</mml:mi></mml:mrow> <mml:annotation>$2\alpha $</mml:annotation></mml:semantics> </mml:math> resolution limit. The aberration compensation and noise filtering features make the SBm-(i)COM suitable for samples that are difficult to focus or those that require minimal electron fluence. SBm-iCOM transfers the same information as SSB ptychography but results in an intrinsic transfer function that enhances low-frequency information.

Journal of MicroscopyVol. 300(2)
Diamond Light Source (GB), University of Oxford (GB), Rosalind Franklin Institute (GB)
Openalex Percentile: Top 6%
Advanced X-ray Imaging Techniques
3.77
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