Is Shorter Better in Oncology Patients, Too? A Retrospective Cohort Study of Short- Versus Long-Course Antibiotic Therapy for Uncomplicated Infections in Solid Tumor Patients Receiving Care in Ambulatory Oncology Clinics
This retrospective cohort study evaluated short- versus long-course antibiotics for uncomplicated infections in ambulatory solid tumor patients. Among 303 patients, outcomes were similar between groups, including infection recurrence, treatment delays, and adverse events. Short-course therapy was not associated with worse outcomes, suggesting it may be a viable alternative.
Authors
- Rachel M. Kenney (ORCID: https://orcid.org/0000-0003-3696-2204)
- Michael P. Veve (ORCID: https://orcid.org/0000-0001-5967-5211)
- Shirish M. Gadgeel (ORCID: https://orcid.org/0000-0001-5240-3811)
- Susan L. Davis (ORCID: https://orcid.org/0000-0001-7521-9486)
- Katelyn M. Patterson
- Christen J Arena (ORCID: https://orcid.org/0009-0002-9787-358X)
- Anita Shallal (ORCID: https://orcid.org/0000-0002-1940-3622)
- George Alangaden (ORCID: https://orcid.org/0000-0001-8076-776X)
- Sage Greenlee (ORCID: https://orcid.org/0000-0002-8206-327X)
- Beisan El-Tatari
- Kristen Lovric
Institutions
- Eugene Applebaum College of Pharmacy and Health Sciences (US)
- Henry Ford Health System (US)
- Wayne State University (US)
- Henry Ford Hospital (US)
- Henry Ford Macomb Hospital (US)
Publication Details
- Journal
- Open Forum Infectious Diseases
- Published
- 2025-08-21
- DOI
- https://doi.org/10.1093/ofid/ofaf505
- Primary Topic
- Neutropenia and Cancer Infections
- Type
- article
- Field-Weighted Citation Impact
- 0.00