Simulation of Repair on Dynamic Patient-Specific Left Atrioventricular Valve Models.
This study demonstrates the feasibility of a dynamic physical simulation platform for preclinical LAVV repair evaluation. Although challenges remain in accurately modeling leaflet closure and chordal mechanics, this proof-of-concept work highlights the platform's potential for refining repair strategies before clinical application, which may be particularly relevant in small and heterogeneous populations with congenital heart disease.
Authors
- Michael D. Quartermain (ORCID: https://orcid.org/0000-0002-0178-6717)
- Devin W. Laurence (ORCID: https://orcid.org/0000-0002-9681-4708)
- Matthew A. Jolley (ORCID: https://orcid.org/0000-0002-5626-0130)
- Christian Herz (ORCID: https://orcid.org/0000-0001-5783-7811)
- Lindsay S. Rogers
- Stephen Ching (ORCID: https://orcid.org/0000-0002-8544-5329)
- Muhammad Nuri
- Jonathan M. Chen
- Elvis C. S. Chen (ORCID: https://orcid.org/0000-0002-4198-3336)
- Patricia Sabin (ORCID: https://orcid.org/0000-0002-5847-8862)
- John Moore (ORCID: https://orcid.org/0000-0003-1968-9760)
- Matthew Daemer
- Christopher N Zelonis
- Yan Wang (ORCID: https://orcid.org/0000-0002-3144-1584)
- Terry M. Peters
Institutions
- Western University (CA)
- Children's Hospital of Philadelphia (US)
Publication Details
- Journal
- PubMed
- Published
- 2025-10-23
- Primary Topic
- Cardiovascular Function and Risk Factors
- Type
- article
- Field-Weighted Citation Impact
- 0.00