[Mechanism of 4-methylcatechol in inhibiting fibroblast-like synoviocyte migration and suppressing inflammatory responses in treatment of rheumatoid arthritis].
4MC not only inhibits the migration of RA-FLS but also mitigates their inflammatory response by suppressing the NF-κB signaling pathway, thereby effectively exerting its anti-RA effects.
Authors
- Dailing Chen
- Qiuru Wang (ORCID: https://orcid.org/0000-0003-4444-6904)
- Tiantian Tang (ORCID: https://orcid.org/0000-0001-6016-4339)
- Peng Wang (ORCID: https://orcid.org/0000-0003-1845-7589)
- Qingwei Ma
- Lei Zhang (ORCID: https://orcid.org/0000-0001-5350-741X)
- Qibin Liu (ORCID: https://orcid.org/0009-0003-1506-4568)
- Changjun Chen (ORCID: https://orcid.org/0000-0002-2794-1551)
- Zhendong Ying
Institutions
- Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
- Shandong Provincial QianFoShan Hospital (CN)
- Affiliated Hospital of Shandong Academy of Medical Sciences (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- PubMed
- Published
- 2025-08-15
- DOI
- https://doi.org/10.7507/1002-1892.202503013
- Primary Topic
- Pharmacological Effects of Natural Compounds
- Type
- article