Primary hyperparathyroidism due to water-clear cell carcinoma of the parathyroid gland: a case report and literature review

This case is particularly significant as it represents the largest water-clear cell carcinoma of the parathyroid gland reported in the literature to date. The patient was closely monitored postoperatively, and at 1-year follow-up, there were no signs of distant metastases or recurrence of hyperparathyroidism. This case underscores the aggressive nature of water-clear cell carcinoma, highlighting the need for early detection and prompt surgical intervention in such rare and potentially life-threatening tumors.

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Publication Details

Journal
Chinese Clinical Oncology
Published
2025-08-21
DOI
https://doi.org/10.21037/cco-25-25
Primary Topic
Parathyroid Disorders and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Primary hyperparathyroidism due to water-clear cell carcinoma of the parathyroid gland: a case report and literature review

Abdullah Esmail, Ebtesam Al-Najjar, Saad Al Awwad, Bayan Khasawneh et al.
2 links
Chinese Clinical Oncology
Parathyroid Disorders and Treatments
article

Primary hyperparathyroidism due to water-clear cell carcinoma of the parathyroid gland: a case report and literature review

Abdullah Esmail, Ebtesam Al-Najjar, Saad Al Awwad, Bayan Khasawneh, Leenah Abdulgader, Ghazi Alharbi
article en

Abstract

This case is particularly significant as it represents the largest water-clear cell carcinoma of the parathyroid gland reported in the literature to date. The patient was closely monitored postoperatively, and at 1-year follow-up, there were no signs of distant metastases or recurrence of hyperparathyroidism. This case underscores the aggressive nature of water-clear cell carcinoma, highlighting the need for early detection and prompt surgical intervention in such rare and potentially life-threatening tumors.

Chinese Clinical OncologyVol. 14(5)
Methodist Hospital (US), Methodist Hospital (US)
Clean water and sanitation
Openalex Percentile: Top 77%
Parathyroid Disorders and Treatments
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