Association of decreased thalamic neurotransmitter level with sensorimotor tract damage in patients with relapsing-remitting multiple sclerosis

Neurotransmitters may play an important role in the pathophysiologic mechanisms of MS. Our study suggests an association between altered GABA and glutamate levels in deep gray-matter and WM microstructural damage in the sensorimotor tract.

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Publication Details

Journal
Quantitative Imaging in Medicine and Surgery
Published
2025-08-21
DOI
https://doi.org/10.21037/qims-2025-219
Primary Topic
Multiple Sclerosis Research Studies
Type
article
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article

Association of decreased thalamic neurotransmitter level with sensorimotor tract damage in patients with relapsing-remitting multiple sclerosis

Wenzhen Zhu, Yu‐Jie Ding, Xiaoxiao Zhang, Yuanhao Li et al.
3 links
Quantitative Imaging in Medicine and Surgery
Multiple Sclerosis Research Studies
article

Association of decreased thalamic neurotransmitter level with sensorimotor tract damage in patients with relapsing-remitting multiple sclerosis

Wenzhen Zhu, Yu‐Jie Ding, Xiaoxiao Zhang, Yuanhao Li, Hongquan Zhu, Zhang Yan, Yan Xie, Shaolong Wu
article en

Abstract

Neurotransmitters may play an important role in the pathophysiologic mechanisms of MS. Our study suggests an association between altered GABA and glutamate levels in deep gray-matter and WM microstructural damage in the sensorimotor tract.

Quantitative Imaging in Medicine and SurgeryVol. 15(9)
Philips (China) (CN), Tongji Hospital (CN), Huazhong University of Science and Technology (CN)
Good health and well-being
Openalex Percentile: Top 69%
Multiple Sclerosis Research Studies
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