Personalized care of paediatric drug‐resistant epilepsy in Africa: A single‐centre pilot study utilizing mobile health and genetic testing
Precision medicine for drug-resistant epilepsy using mHealth and genetics may show use in a resource-limited setting. This study, the first demonstration of precision medicine in an African paediatric setting, informs the development of diagnostic testing and provides novel insights into the lives and genetics of affected children.
Authors
- Jo M. Wilmshurst (ORCID: https://orcid.org/0000-0001-7328-1796)
- Alina Esterhuizen (ORCID: https://orcid.org/0000-0002-6976-9489)
- Elin Haf Davies (ORCID: https://orcid.org/0000-0002-4987-0088)
- Karen Fieggen (ORCID: https://orcid.org/0000-0002-2910-6306)
- Irene Farisai Muchada
- Ian S. Olivier (ORCID: https://orcid.org/0000-0001-8013-070X)
- Sandra Komarzynski (ORCID: https://orcid.org/0000-0003-3886-6494)
- Richard J. Burman (ORCID: https://orcid.org/0000-0003-3107-7871)
- C McIntosh
Institutions
- National Health Laboratory Service (ZA)
- University of Cape Town (ZA)
- Wrexham Maelor Hospital (GB)
- Groote Schuur Hospital (ZA)
- Red Cross War Memorial Children's Hospital (ZA)
Publication Details
- Journal
- Developmental Medicine & Child Neurology
- Published
- 2025-08-20
- DOI
- https://doi.org/10.1111/dmcn.16478
- Citations
- 2
- Primary Topic
- Epilepsy research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 2.94
Funders
- Newton Fund
- National Research Foundation
- South African Medical Research Council
- University of Cape Town
- Medical Research Council