Characterization of Bioactive CompoundsExtracted from Bacteria AgainstBiomphalaria alexandrina

The parasitic illness schistosomiasis causes significant harm to human organs upon infection.The most effective strategy for schistosomiasis management is snail management.The current study's goal is to determine which bacterial species had a lethal impact on Biomphalaria alexandrina (B.alexandrina) as a potential host for Schistosoma manosni (S. manosni).24 bacterial filtrates were applied for 24 hours to examine their impact on the percentage of snails' mortality at a level of 1000 g/ml.The molluscicidal impact of the most efficient compounds derived from bacterial filtrates was expressed as (LC 10 , LC 25 , LC 50 , and LC 90 ).The effects of promising compounds were evaluated versus Daphnia pulex (D. pulex) to investigate their toxic impact.Biochemical parameters were evaluated to test the impact of the most promising purified compounds.Based on H 1 -NMR, FTIR, and mass data, the proposed chemical structures of the isolated compounds were defined.Staphylococcus aureus (S. aureus) and Escherichia coli (E.coli) filtrates have the most effective impact on B. alexandrina.Sub-lethal doses (LC 10 and LC 25 ) of purified compounds were reported to have a dramatic impact on liver enzymes and a minimal impact on other tested parameters.A notable variation in the protein pattern of the treated snails was observed using efficient bacterial molecules versus the control.The derived compounds have been reported to have minimal toxicity on D. pulex.The proposed name of the identified compound from S. aureus was (5-sec-Butyl-4,5,6,7-tetrahydro-1H-indol-3-yl)-acetaldehyde, while the proposed name of the identified compound from E. coli was 2-Isobutyl-6-(4-methyl-pentyl)-phenylamine to be produced for future potential uses.