Understanding the impact of multimorbidity, medications and frailty on zoledronic acid efficacy in treating osteoporosis among older adults

The study emphasizes that identifying barriers to treatment success is crucial for optimizing OP management. ZA improves BMD and reduces fractures, even in frail older adults with multimorbidity, supporting its use across diverse patient profiles and stressing the need for personalized treatment strategies.

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Publication Details

Journal
British Journal of Clinical Pharmacology
Published
2025-08-20
DOI
https://doi.org/10.1002/bcp.70243
Primary Topic
Bone health and osteoporosis research
Type
article
Field-Weighted Citation Impact
0.00
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article

Understanding the impact of multimorbidity, medications and frailty on zoledronic acid efficacy in treating osteoporosis among older adults

Münevver Özcan, Serdar Ceylan, Burcu Balam Doğu, Berşan Özcan et al.
British Journal of Clinical Pharmacology
Bone health and osteoporosis research
article

Understanding the impact of multimorbidity, medications and frailty on zoledronic acid efficacy in treating osteoporosis among older adults

Münevver Özcan, Serdar Ceylan, Burcu Balam Doğu, Berşan Özcan, Merve Güner, Meltem Gulhan Halil, Cafer Balcı, Mustafa Cankurtaran
article en

Abstract

The study emphasizes that identifying barriers to treatment success is crucial for optimizing OP management. ZA improves BMD and reduces fractures, even in frail older adults with multimorbidity, supporting its use across diverse patient profiles and stressing the need for personalized treatment strategies.

British Journal of Clinical PharmacologyVol. 91(12)
Hacettepe University (TR)
Openalex Percentile: Top 73%
Bone health and osteoporosis research
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