Prognostic and functional role of PPAR-alpha and SNP receptor (Leu162Val) in acute coronary syndrome: a potential novel target

The present study demonstrated a relationship between the concentration of PPAR-alpha and the genetic polymorphism of Leu162Val (rs1800206) SNP and acute coronary syndrome with a decrease in the concentration of PPAR-alpha and the predominance of the recessive gene and the recessive allele in patients compared to healthy individuals.

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Publication Details

Journal
Journal of Genetic Engineering and Biotechnology
Published
2025-08-21
DOI
https://doi.org/10.1016/j.jgeb.2025.100555
Primary Topic
Peroxisome Proliferator-Activated Receptors
Type
article
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article

Prognostic and functional role of PPAR-alpha and SNP receptor (Leu162Val) in acute coronary syndrome: a potential novel target

Hassan H. Al-Saeed, Sami Mekhlif Mishlish, Abdullah Abdulsattar Raeef
Journal of Genetic Engineering and Biotechnology
Peroxisome Proliferator-Activated Receptors
article

Prognostic and functional role of PPAR-alpha and SNP receptor (Leu162Val) in acute coronary syndrome: a potential novel target

Hassan H. Al-Saeed, Sami Mekhlif Mishlish, Abdullah Abdulsattar Raeef
article en

Abstract

The present study demonstrated a relationship between the concentration of PPAR-alpha and the genetic polymorphism of Leu162Val (rs1800206) SNP and acute coronary syndrome with a decrease in the concentration of PPAR-alpha and the predominance of the recessive gene and the recessive allele in patients compared to healthy individuals.

Journal of Genetic Engineering and BiotechnologyVol. 23(4)
University of Anbar (IQ), University of Al Maarif (IQ), Nahrain University (IQ)
Good health and well-being
Openalex Percentile: Top 81%
Peroxisome Proliferator-Activated Receptors
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