Redefining Thyroid Nodule Evaluation: Demographics, Misleading Symptoms, and Diagnostic Challenges. Insights From a Multicenter Study
A third of TNs are diagnosed during US prompted by LS, yet only NMs are associated with distinct nodule characteristics. Dysphagia and dysphonia were nonspecific and more related to gastroesophageal reflux disease than TNs. These findings support caution against overuse of US. Demographics, nodule features, and location should guide clinical suspicion and imaging decisions to avoid unnecessary imaging and interventions.
Authors
- Salvatore Cannavò (ORCID: https://orcid.org/0000-0001-8779-7283)
- Luca Rossi (ORCID: https://orcid.org/0000-0003-3288-9134)
- Marsida Teliti (ORCID: https://orcid.org/0009-0007-4606-8923)
- Carlo Cappelli (ORCID: https://orcid.org/0000-0003-4317-1232)
- Elena Petrosino
- Paolo Caccavale (ORCID: https://orcid.org/0000-0003-0155-8906)
- Mario Rotondi (ORCID: https://orcid.org/0000-0001-6464-2334)
- Spyridon Chytiris (ORCID: https://orcid.org/0000-0002-7999-3505)
- Martina Laganà
- Rosaria Maddalena Ruggeri (ORCID: https://orcid.org/0000-0001-8899-684X)
- Laura Croce
Institutions
- University of Messina (IT)
- University of Pavia (IT)
- Istituti Clinici Scientifici Maugeri (IT)
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia (IT)
- University of Brescia (IT)
Publication Details
- Journal
- Endocrine Practice
- Published
- 2025-08-21
- DOI
- https://doi.org/10.1016/j.eprac.2025.08.007
- Citations
- 1
- Primary Topic
- Thyroid Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.29
Funders
- Ministero della Salute