Gliptin-induced Pemphigus

This case highlights the development of gliptin-induced pemphigus in a patient shortly after initiating gliptin therapy for diabetes. It is essential to differentiate drug-induced pemphigus from idiopathic cases, as they can be clinically and histopathologically indistinguishable. A detailed medical history, including medication use, is crucial to identifying drug-induced conditions. The time interval between initiating the suspected drug and the onset of skin manifestations can vary widely from case to case. Improvement of the lesions following drug cessation confirms the diagnosis of drug-induced pemphigus.

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Publication Details

Journal
Annals of African Medicine
Published
2025-08-20
DOI
https://doi.org/10.4103/aam.aam_162_25
Citations
1
Primary Topic
Autoimmune Bullous Skin Diseases
Type
article
Field-Weighted Citation Impact
1.47
Controls
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article

Gliptin-induced Pemphigus

Ashwini Dattatray Mundhe, Shelly Arora, Avinash Jadhav
1 citations
Annals of African Medicine
Autoimmune Bullous Skin Diseases
1.47
article

Gliptin-induced Pemphigus

Ashwini Dattatray Mundhe, Shelly Arora, Avinash Jadhav
article en
1 citations

Abstract

This case highlights the development of gliptin-induced pemphigus in a patient shortly after initiating gliptin therapy for diabetes. It is essential to differentiate drug-induced pemphigus from idiopathic cases, as they can be clinically and histopathologically indistinguishable. A detailed medical history, including medication use, is crucial to identifying drug-induced conditions. The time interval between initiating the suspected drug and the onset of skin manifestations can vary widely from case to case. Improvement of the lesions following drug cessation confirms the diagnosis of drug-induced pemphigus.

Annals of African Medicine
Dr. D. Y. Patil Medical College, Hospital and Research Centre (IN), Dr. D.Y. Patil Vidyapeeth, Pune (IN)
Openalex Percentile: Top 16%
Autoimmune Bullous Skin Diseases
1.47
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