Elevated FDG uptake in non-tumorous lung regions does not predict immune checkpoint inhibitor–related pneumonitis in lung cancer patients
This is the largest study on the association of pretreatment radioligand uptake of the non-tumorous lung and the risk of a cinrPneumonitis. Our results showed no significant association between elevated pretreatment radioligand uptake of non-tumorous lung tissue on FDG-PET/CT and the development of cinrPneumonitis.
Authors
- Julia Walter (ORCID: https://orcid.org/0000-0003-4304-6159)
- Lena M. Unterrainer
- Maria Ingenerf (ORCID: https://orcid.org/0000-0001-6465-4597)
- Thomas Pfluger
- Lucie Heinzerling (ORCID: https://orcid.org/0000-0002-9074-8017)
- Friederike Völter (ORCID: https://orcid.org/0000-0001-6157-0363)
- Amanda Tufman (ORCID: https://orcid.org/0000-0001-9243-9050)
- Gabriel T. Sheikh (ORCID: https://orcid.org/0000-0002-7026-9203)
- Maurice M. Heimer (ORCID: https://orcid.org/0000-0002-0940-0161)
- Matthias Brendel (ORCID: https://orcid.org/0000-0002-6522-4895)
- Diego Kauffmann‐Guerrero (ORCID: https://orcid.org/0000-0003-1471-3290)
- Blerina Resuli (ORCID: https://orcid.org/0000-0003-2024-2771)
- Lukas Wehlte
- Lea Daisenberger
Institutions
- German Center for Neurodegenerative Diseases (DE)
- LMU Klinikum (DE)
- Munich Cluster for Systems Neurology (DE)
- German Center for Lung Research (DE)
- Comprehensive Cancer Center Erlangen (DE)
- DKFZ-ZMBH Alliance (DE)
- Molecular Theranostics (United States) (US)
- Ludwig-Maximilians-Universität München (DE)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-08-20
- DOI
- https://doi.org/10.3389/fonc.2025.1563030
- Citations
- 1
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 1.05
Funders
- Deutsche Forschungsgemeinschaft
- Bundesministerium für Bildung und Forschung