The role of the 3′-UTR of the chemokine receptor CCR2 and hnRNPA0 in regulating mRNA stability and subcellular distribution in human CD4+ T cells
These results show that the CCR2 3'-UTR plays an important role in post-transcriptional regulation and may provide a novel approach to regulating CCR2 activity in inflammatory or infectious diseases.
Authors
- Yunus Yükselten (ORCID: https://orcid.org/0000-0003-4944-0819)
- Lingyun Wang (ORCID: https://orcid.org/0000-0001-5095-8784)
- Richard E. Sutton (ORCID: https://orcid.org/0000-0001-7418-2378)
- Hanan Wishah
Institutions
- Yale University (US)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-08-20
- DOI
- https://doi.org/10.3389/fimmu.2025.1655273
- Citations
- 1
- Primary Topic
- RNA Research and Splicing
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- Yale University
- National Institutes of Health
- National Cancer Institute
- National Institute of Allergy and Infectious Diseases