Deciphering prognostic markers in gastric signet ring cell carcinoma: Human epidermal growth factor receptor 2 and other key factors
These findings highlight the aggressive nature of SRCC with advanced disease stage, elevated tumor markers, and lymphovascular invasion contributing to poor outcomes. HER2 expression, though infrequent, may indicate worse prognosis, reinforcing the role of surgical intervention in survival improvement.
Authors
- R. Salama (ORCID: https://orcid.org/0000-0002-1102-9306)
- Maha Othman (ORCID: https://orcid.org/0000-0001-7562-203X)
- Nancy H Amin
- Neveen Tahoun (ORCID: https://orcid.org/0000-0002-0562-0335)
- Noura A. A. Ebrahim (ORCID: https://orcid.org/0009-0001-7037-680X)
- Ayman M. Arafat (ORCID: https://orcid.org/0000-0003-3069-8385)
Institutions
- Cairo University (EG)
- Children Cancer Hospital (EG)
- Ras al-Khaimah Medical and Health Sciences University (AE)
Publication Details
- Journal
- World Journal of Clinical Oncology
- Published
- 2025-08-20
- DOI
- https://doi.org/10.5306/wjco.v16.i8.107987
- Primary Topic
- Gastric Cancer Management and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00