Patient-derived organoids as a model to study tubo-ovarian carcinoma: a pathologist’s perspective
This study highlights the need for a multidisciplinary collaboration in both clinical and research settings to establish patient-derived organoids. It emphasises the pivotal contribution of pathologists in meticulous sampling and organoid characterisation. The integration of diverse expertise is essential for maximising the potential of organoids as preclinical tools, advancing our understanding of tubo-ovarian carcinoma, and ultimately improving patient outcomes.
Authors
- Catarina Alves‐Vale (ORCID: https://orcid.org/0000-0002-5728-7001)
- Paula Borralho (ORCID: https://orcid.org/0000-0002-8556-2090)
- João Paulo S. Fernandes (ORCID: https://orcid.org/0000-0002-9089-273X)
- Beatriz Galvão (ORCID: https://orcid.org/0009-0006-3127-3863)
- Ana Rita Silvestre
- Maria Carmo‐Fonseca (ORCID: https://orcid.org/0000-0002-3402-7143)
- Noélia Custódio (ORCID: https://orcid.org/0000-0001-9230-9870)
- Bei Li (ORCID: https://orcid.org/0000-0003-0876-2248)
- José Silva Pereira (ORCID: https://orcid.org/0000-0003-0394-6793)
Institutions
- University of Lisbon (PT)
- Companhia União Fabril (PT)
- Hospital de Egas Moniz (PT)
- Angiologica (Italy) (IT)
Publication Details
- Journal
- Journal of Ovarian Research
- Published
- 2025-08-20
- DOI
- https://doi.org/10.1186/s13048-025-01766-4
- Primary Topic
- Ovarian cancer diagnosis and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- AstraZeneca
- Gilead Sciences
- Universidade de Lisboa
- Fundação para a Ciência e a Tecnologia