Unusual 131I Uptake in Talus May Reveal Distant Papillary Thyroid Cancer Metastasis With Anaplastic Transformation
Talus metastasis is rarely observed on a 131 I whole-body scan (WBS). We report a case of abnormal 131 I uptake in the talus on the post-therapeutic WBS in a 54-year-old woman with papillary thyroid cancer (PTC). The patient received 2 courses of radioactive 131 I therapy (RAIT) after the thyroid surgery. WBS after the second dose of RAIT showed that 131 I uptake in the right talus declined than the last post-therapeutic WBS presented. The talus lesion was confirmed to be metastatic PTC with anaplastic transformation by pathologic examination and immunohistochemistry.
Authors
- Guoqiang Wang (ORCID: https://orcid.org/0000-0001-5732-8144)
- Xufu Wang (ORCID: https://orcid.org/0000-0002-0849-5429)
- Jiao Li (ORCID: https://orcid.org/0000-0003-4429-7793)
- Yingying Zhang (ORCID: https://orcid.org/0000-0003-3819-5467)
- Chenghui Lu (ORCID: https://orcid.org/0000-0003-0000-9032)
Institutions
- Qingdao University (CN)
- Affiliated Hospital of Qingdao University (CN)
Publication Details
- Journal
- Clinical Nuclear Medicine
- Published
- 2025-08-20
- DOI
- https://doi.org/10.1097/rlu.0000000000006102
- Primary Topic
- Thyroid Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00