Value of urinary lipoarabinomannan levels for tuberculosis diagnosis and monitoring of therapy
Urinary LAM serves as a dual-role biomarker, providing moderate diagnostic sensitivity and dynamic monitoring signals reflecting early bacillary response to therapy. The PreLAM+ΔLAM model enables early treatment response assessment for personalized therapy.
Authors
- Yiqun Xiong
- Zhihong Shen
- Bo Dong (ORCID: https://orcid.org/0000-0002-6965-4585)
- Dongliang Zhang (ORCID: https://orcid.org/0000-0002-6303-7404)
- Hongxia Wei (ORCID: https://orcid.org/0009-0008-2153-9132)
- Ying Zhu (ORCID: https://orcid.org/0000-0001-8874-6904)
- Ying Wang (ORCID: https://orcid.org/0000-0001-9628-7904)
- Yang Che
Institutions
- Lyceum of the Philippines University (PH)
- University of Batangas (PH)
- Batangas State University (PH)
- Ningbo Center for Disease Control and Prevention (CN)
- Ningbo No. 2 Hospital (CN)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2025-08-20
- DOI
- https://doi.org/10.3389/fmicb.2025.1653031
- Primary Topic
- Tuberculosis Research and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Zhejiang Province