Rare primary anorectal malignant melanoma presenting with painless hematochezia: a case report
This case underscores that ARMM can be clinically indistinguishable from rectal carcinoma, posing a high risk of misdiagnosis. It highlights the critical role of histopathology and immunohistochemistry (IHC) in definitive differentiation, emphasizing the necessity of accurate diagnosis through IHC. Finally, it demonstrates the evolving treatment paradigm from extensive surgery toward a multidisciplinary approach integrating radical resection with adjuvant immunotherapy, reflecting advances in molecular insights and ameliorated outcomes.
Authors
- Yu‐Liang Zou (ORCID: https://orcid.org/0000-0002-1884-1532)
- Yuchun Zhong
- Wei Xu (ORCID: https://orcid.org/0000-0003-4208-7477)
- Xiao Hu (ORCID: https://orcid.org/0000-0003-1128-4099)
- Lihong Peng (ORCID: https://orcid.org/0000-0002-3905-7085)
Institutions
- Nanchang University (CN)
- Second Affiliated Hospital of Nanchang University (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-08-20
- DOI
- https://doi.org/10.3389/fonc.2025.1640063
- Primary Topic
- Cutaneous Melanoma Detection and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China