Development of a predictive model for radiation pneumonitis based on plasma exosomal miR-200b-5p
The combination of lung V5 >46.36%, MLD >1120 cGy, and miR-200b-5p expression <0.445 can be used to effectively predict the occurrence of SRP in locally advanced NSCLC patients. This model can aid in the early identification of patients at high risk for RP, allowing for personalized treatment adjustments and improved patient outcomes.
Authors
- Yuetong Li (ORCID: https://orcid.org/0009-0004-0320-0953)
- Shuwei Zhai
- Liang Xu (ORCID: https://orcid.org/0000-0001-9196-4232)
- Haihua Yang (ORCID: https://orcid.org/0000-0001-5549-8633)
- Xiaoye Wang (ORCID: https://orcid.org/0000-0003-0355-6859)
- Huaiyu Wang (ORCID: https://orcid.org/0000-0002-7189-9944)
- Qianfei Zhao
- Yajun Emily Zhu
- Shuhao Que
- Enhui Dai
- Wei Feng (ORCID: https://orcid.org/0009-0009-5385-5831)
Institutions
- Wenzhou Medical University (CN)
- Zhejiang Cancer Hospital (CN)
- The First People's Hospital of Changzhou (CN)
- Cancer Hospital of Chinese Academy of Medical Sciences (CN)
- Taizhou University (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-08-20
- DOI
- https://doi.org/10.3389/fonc.2025.1516348
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00