Predicted skeletal muscle index as a scalable marker for sarcopenia risk and mortality in older Chinese adults
pSMI strongly predicts sarcopenia and mortality in older Chinese adults. To our knowledge, this represents the first large-scale validation of pSMI's prognostic value for mortality risk independent of baseline sarcopenia in a nationally representative older Chinese cohort. As a blood-based biomarker, pSMI may serve as a practical screening tool and prognostic marker, facilitating timely interventions such as nutritional support and resistance exercise.
Authors
- Qiaorong Dong
- L Y
- Xiaojing Zhao (ORCID: https://orcid.org/0000-0001-5571-9192)
- Huanhuan Wang (ORCID: https://orcid.org/0000-0001-6935-0760)
- Y. Qi (ORCID: https://orcid.org/0000-0002-6663-305X)
- Min Zhang (ORCID: https://orcid.org/0000-0002-2662-1142)
- Lan Huang (ORCID: https://orcid.org/0009-0002-4379-3795)
- Ya Liu (ORCID: https://orcid.org/0009-0005-5866-3178)
Institutions
- Chengde Medical University (CN)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2025-08-20
- DOI
- https://doi.org/10.3389/fmed.2025.1640410
- Primary Topic
- Nutrition and Health in Aging
- Type
- article
- Field-Weighted Citation Impact
- 0.00