Cluster analysis of hotspots and research trends of epirubicin-induced cardiotoxicity: a bibliometric study

This bibliometric study, based on cluster analysis, identified four research hotspots including mechanisms of cardiotoxicity, clinical applications of chemotherapy regimens, combination therapies and pharmacokinetics, formulation advancements and cardioprotective strategies. Future research directions should prioritize the development of AI-driven risk prediction models, integration of multi-omics biomarkers into clinical workflows, and establishment of international cardio-oncology consortiums to enhance personalized cardioprotective strategies and optimize patient outcomes.