Genetic etiology and pregnancy outcomes of fetal hyperechoic kidneys: a retrospective analysis
CMA is recommended when prenatal ultrasound indicates fetal hyperechoic kidneys. For fetuses with normal CNVs and persistent hyperechoic kidneys, WES is advisable to exclude rare monogenic disorders. In cases of hyperechoic kidneys alongside other ultrasound abnormalities, the live birth rate and prognosis tend to be poor; thus, early genetic screening is essential to guide pregnancy management effectively.
Authors
- Meiying Cai (ORCID: https://orcid.org/0000-0002-7431-2475)
- Liangpu Xu (ORCID: https://orcid.org/0000-0001-8815-2735)
- Zhijie Xiao (ORCID: https://orcid.org/0000-0002-9050-8865)
- Lin Zheng (ORCID: https://orcid.org/0000-0001-6178-1558)
- Hailong Huang
- Na Lin
Institutions
- Fujian Medical University (CN)
- Second Affiliated Hospital of Fujian Medical University (CN)
Publication Details
- Journal
- Frontiers in Pediatrics
- Published
- 2025-08-20
- DOI
- https://doi.org/10.3389/fped.2025.1496381
- Primary Topic
- Prenatal Screening and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Fujian Province