Optimization of ivacaftor-loaded solid lipid nanoparticles for solubility enhancement

This delivery system presented development of stable nanoparticle formulation exhibiting sustained release pattern, which may contribute to therapeutic outcomes in comparison with drug alone. The outcomes of the research highlighted its potential as an efficient therapeutic strategy for CF management.

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Journal
Frontiers in Pharmacology
Published
2025-08-20
DOI
https://doi.org/10.3389/fphar.2025.1619481
Primary Topic
Advancements in Transdermal Drug Delivery
Type
article
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article

Optimization of ivacaftor-loaded solid lipid nanoparticles for solubility enhancement

Bhupendra Gopalbhai Prajapati, Himanshu Paliwal, Akshay Parihar
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Frontiers in Pharmacology
Advancements in Transdermal Drug Delivery
article

Optimization of ivacaftor-loaded solid lipid nanoparticles for solubility enhancement

Bhupendra Gopalbhai Prajapati, Himanshu Paliwal, Akshay Parihar
article en

Abstract

This delivery system presented development of stable nanoparticle formulation exhibiting sustained release pattern, which may contribute to therapeutic outcomes in comparison with drug alone. The outcomes of the research highlighted its potential as an efficient therapeutic strategy for CF management.

Frontiers in PharmacologyVol. 16
Marwadi University (IN), Parul University (IN), Ganpat University (IN), Chitkara University (IN), Institute of Chartered Financial Analysts of India (IN), Silpakorn University (TH)
Openalex Percentile: Top 84%
Advancements in Transdermal Drug Delivery
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Optimization of ivacaftor-loaded solid lipid nanoparticles for solubility enhancement — Bhupendra Gopalbhai Prajapati, Himanshu Paliwal, et al. · Frontiers in Pharmacology (2025) | TGRS Research Map | TGRS