Ethical dimensions and societal implications: ensuring the social responsibility of CRISPR technology

CRISPR-Cas9 is a breakthrough genome-editing platform that can cut chosen DNA sequences with unprecedented speed, accuracy, and affordability. By reprogramming a single guide RNA, researchers now alter gene function, correct pathogenic variants, or introduce novel traits. Earlier tools such as zinc-finger nucleases and TALENs performed similar tasks but were significantly more complex and costly. Yet CRISPR's very power raises urgent ethical concerns: Who controls its use, and how can society prevent germ-line enhancement, eugenic selection, or unequal access that favors wealthy nations and patients? A well-publicized case of embryo editing already showed how premature, unregulated experiments can erode public trust. This perspective therefore frames CRISPR's scientific promise alongside its social responsibilities, arguing that proactive, globally coordinated governance is essential to unlock benefits while preventing new forms of genetic inequality.

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Publication Details

Journal
Frontiers in Genome Editing
Published
2025-08-20
DOI
https://doi.org/10.3389/fgeed.2025.1593172
Citations
3
Primary Topic
CRISPR and Genetic Engineering
Type
article
Field-Weighted Citation Impact
2.42
Controls
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article

Ethical dimensions and societal implications: ensuring the social responsibility of CRISPR technology

Irfan Biswas
3 citations
Frontiers in Genome Editing
CRISPR and Genetic Engineering
2.42
article

Ethical dimensions and societal implications: ensuring the social responsibility of CRISPR technology

Irfan Biswas
article en
3 citations

Abstract

CRISPR-Cas9 is a breakthrough genome-editing platform that can cut chosen DNA sequences with unprecedented speed, accuracy, and affordability. By reprogramming a single guide RNA, researchers now alter gene function, correct pathogenic variants, or introduce novel traits. Earlier tools such as zinc-finger nucleases and TALENs performed similar tasks but were significantly more complex and costly. Yet CRISPR's very power raises urgent ethical concerns: Who controls its use, and how can society prevent germ-line enhancement, eugenic selection, or unequal access that favors wealthy nations and patients? A well-publicized case of embryo editing already showed how premature, unregulated experiments can erode public trust. This perspective therefore frames CRISPR's scientific promise alongside its social responsibilities, arguing that proactive, globally coordinated governance is essential to unlock benefits while preventing new forms of genetic inequality.

Frontiers in Genome EditingVol. 7
University of Massachusetts Chan Medical School (US), University of Rhode Island (US), Shrewsbury College (GB)
Openalex Percentile: Top 10%
CRISPR and Genetic Engineering
2.42
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