The Role of Cannabis in Modulating Female Sexual Desire: A Narrative Review

As cannabis legalization expands across the globe, growing public interest has turned toward its potential effects on women’s sexual health—particularly in areas of desire, arousal, and satisfaction. Historically, female sexual function has been underexplored, with minimal attention given to how plant-based substances like cannabis may influence libido and intimacy. With mounting anecdotal accounts and a growing body of scientific inquiry, this topic demands greater investigative rigor. This narrative review synthesizes current research on cannabis and female sexual desire, emphasizing low- to moderate-dose use. It examines neurobiological mechanisms, including the role of the endocannabinoid system (ECS), and integrates observational studies and patient-reported outcomes to identify trends, inconsistencies, and clinical relevance. The review also highlights gaps in the literature and the need for robust randomized controlled trials. As clinicians adopt integrative approaches to sexual health, understanding cannabis’s nuanced impact on female desire could shape future therapeutic strategies.