Hirsutine ameliorates obesity cardiomyopathy through the induction of mitophagy by stablizing parkin
Background and Purpose: Hirsutine, a potent indole alkaloid extracted from U. rhynchophylla, has been shown to ameliorate cardiac insulin resistance in high-fat diet (HFD)-induced diabetic mice. However, the underlying regulatory mechanisms remain inc
Authors
- Jianshe Ma (ORCID: https://orcid.org/0000-0003-3432-3468)
- Lu Ding (ORCID: https://orcid.org/0000-0001-7547-2844)
- Junming Fan (ORCID: https://orcid.org/0000-0003-1425-6712)
- Peifeng Jin (ORCID: https://orcid.org/0000-0002-4933-9406)
- Zelei Ye
- Yi Chen (ORCID: https://orcid.org/0000-0003-3452-8412)
- Hao Zhou (ORCID: https://orcid.org/0009-0000-1276-0080)
- Jingwen Wang (ORCID: https://orcid.org/0000-0002-1405-4697)
- Zichen Gao
- Shijia Chen (ORCID: https://orcid.org/0000-0002-8361-2947)
- Mengyuan Song
- Ru Zhao (ORCID: https://orcid.org/0000-0002-8894-6807)
- Ahmad Naqib Shuid (ORCID: https://orcid.org/0000-0002-8907-4350)
Institutions
- Universiti Sains Malaysia (MY)
- Wenzhou Medical University (CN)
- First Affiliated Hospital of Wenzhou Medical University (CN)
- Hospital Universiti Sains Malaysia (MY)
Publication Details
- Published
- 2025-08-20
- DOI
- https://doi.org/10.22541/au.175569080.03236966/v1
- Primary Topic
- Natural Antidiabetic Agents Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00