Development of a multi-indicator risk prediction model for cervical cancer associated with benzo[a]pyrene and nicotine exposure: A multi-omics study integrating toxicological analyses and molecular docking
Risk prediction models based on multi-omics data and machine learning algorithms provide potential reference targets for prognosis prediction and personalised treatment of cervical cancer patients. The results of this study provide important insights into the understanding of the health risks of cervical cancer associated with Benzo[a]pyrene and Nicotine exposures and the development of preventive and therapeutic strategies for cervical cancer, which may contribute to the development of precision medicine for cervical cancer.
Authors
- Hongting Zhao
- Qingling Ren (ORCID: https://orcid.org/0000-0002-7383-9873)
- Yihan Zhang (ORCID: https://orcid.org/0000-0002-7558-4069)
- Ning Li (ORCID: https://orcid.org/0000-0002-4485-998X)
- Xiu Li (ORCID: https://orcid.org/0000-0003-0403-1923)
- Yu Si (ORCID: https://orcid.org/0000-0002-7440-5890)
- Yating Xu
Institutions
- Nanjing University of Chinese Medicine (CN)
- Hubei University of Chinese Medicine (CN)
- Jiangsu Province Hospital (CN)
Publication Details
- Journal
- Ecotoxicology and Environmental Safety
- Published
- 2025-08-20
- DOI
- https://doi.org/10.1016/j.ecoenv.2025.118895
- Primary Topic
- Carcinogens and Genotoxicity Assessment
- Type
- article
- Field-Weighted Citation Impact
- 0.00